Amylyx Pharmaceuticals, Inc.

AMLX · NasdaqGS · Stock · Healthcare
$27.03
+0.67% today
Delayed price,

What Amylyx Pharmaceuticals does

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

Key facts

Sector
Healthcare
Industry
Drug Manufacturers - Specialty & Generic
Market cap
$3.39B
P/E (ttm)
—
Forward P/E
-23.5
Dividend yield
0.00%
Beta
-0.09
Profit margin
0.0%
Employees
136
Headquarters
Cambridge, MA, United States
Exchange
NasdaqGS
Website

Performance

1 Month
-16.6%
3 Months
+52.3%
6 Months
+47.2%
1 Year
+80.8%
5 Years
-17.8%
$10.8352-week range$41.14
Biggest setback — last 12 months
-30.5%
17 Aug 2026 → 12 Oct 2026
Fell from $38.66 to $26.85 — its sharpest sustained decline this year.
Biggest run-up — last 12 months
+238.5%
29 Dec 2025 → 17 Aug 2026
Ran from $11.42 to $38.66 — its strongest sustained advance this year.

Price outlook — trend & volatility model

● Trend: Above long-term trend
Price sits above its 200-day average, but the shorter-term averages are not cleanly aligned above/below it.
HorizonBear case (−1σ)Base caseBull case (+1σ)
1 Month$20.76 (-23.2%)$27.03$35.19 (+30.2%)
3 Months$17.12 (-36.7%)$27.03$42.68 (+57.9%)
6 Months$14.17 (-47.6%)$27.03$51.57 (+90.8%)
12 Months$10.84 (-59.9%)$27.03$67.39 (+149.3%)
Statistical, not machine-learning: a random-walk (no assumed drift) volatility model built from this ticker's own realized price history, plus a purely descriptive moving-average trend read. Illustrative only — not a price target and not financial advice. The bear and bull cases sit one standard deviation (1σ) below and above today's price, a range that covers about 68% of the outcomes the model treats as plausible, not a 68% chance of either case. Annualized volatility used: 91.4%, blended from this ticker's own 3-month and 1-year realized price history. Base case is deliberately flat — this quantifies a possible range, not a directional prediction. See the full model, including wider (≈95%) bands →

Comparable companies

Recent insider activity

Sold 30,000 shares at $27.70 — MILNE GEORGE M JR, Director · 2026-10-07
Sold 10,028 shares at $33.09 — Bedrosian Camille L, Chief Medical Officer · 2026-09-14
Sold 10,810 shares at $33.23 — FRATES JAMES M, Chief Financial Officer · 2026-09-14
Sold 9,536 shares at $33.34 — Mazzariello Gina, Chief Legal Officer · 2026-09-14
Sold 30,464 shares at $33.16 — Klee Justin B., Co-Chief Executive Officer · 2026-09-14
Source: SEC Form 4 filings. An "acquired" entry with no price is typically a stock award or option exercise rather than an open-market purchase. Search all insider trades →

Learn the basics

Prices and company data are delayed reference figures from public sources (Yahoo Finance, SEC EDGAR) and may be inaccurate or out of date. This page is informational only — it is not investment advice or a recommendation to buy or sell any security. Past performance does not indicate future results.