Castle Biosciences, Inc.

CSTL · NasdaqGM · Stock · Healthcare
$33.11
+0.70% today
Delayed price,

What Castle Biosciences does

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma. The company offers its products to dermatology and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.

Key facts

Sector
Healthcare
Industry
Diagnostics & Research
Market cap
$1.01B
P/E (ttm)
—
Forward P/E
-36.3
Dividend yield
0.00%
Beta
0.94
Profit margin
-5.4%
Employees
1,002
Headquarters
Friendswood, TX, United States
Exchange
NasdaqGM

Performance

1 Month
-6.3%
3 Months
+37.0%
6 Months
+32.2%
1 Year
+49.5%
5 Years
-19.9%
$17.7252-week range$44.28
Biggest setback — last 12 months
-54.7%
19 Jan 2026 → 11 May 2026
Fell from $42.24 to $19.13 — its sharpest sustained decline this year.
Biggest run-up — last 12 months
+90.8%
13 Oct 2025 → 19 Jan 2026
Ran from $22.14 to $42.24 — its strongest sustained advance this year.

Price outlook — trend & volatility model

● Trend: Above long-term trend
Price sits above its 200-day average, but the shorter-term averages are not cleanly aligned above/below it.
HorizonBear case (−1σ)Base caseBull case (+1σ)
1 Month$28.23 (-14.7%)$33.11$38.83 (+17.3%)
3 Months$25.12 (-24.1%)$33.11$43.64 (+31.8%)
6 Months$22.40 (-32.3%)$33.11$48.93 (+47.8%)
12 Months$19.06 (-42.4%)$33.11$57.53 (+73.7%)
Statistical, not machine-learning: a random-walk (no assumed drift) volatility model built from this ticker's own realized price history, plus a purely descriptive moving-average trend read. Illustrative only — not a price target and not financial advice. The bear and bull cases sit one standard deviation (1σ) below and above today's price, a range that covers about 68% of the outcomes the model treats as plausible, not a 68% chance of either case. Annualized volatility used: 55.2%, blended from this ticker's own 3-month and 1-year realized price history. Base case is deliberately flat — this quantifies a possible range, not a directional prediction. See the full model, including wider (≈95%) bands →

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Prices and company data are delayed reference figures from public sources (Yahoo Finance, SEC EDGAR) and may be inaccurate or out of date. This page is informational only — it is not investment advice or a recommendation to buy or sell any security. Past performance does not indicate future results.