MBX Biosciences, Inc.

MBX · NasdaqGS · Stock · Healthcare
$48.82
-0.37% today
Delayed price,

What MBX Biosciences does

MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is Canvuparatide (MBX 2109), a parathyroid hormone peptide prodrug, which is in Phase 3 clinical trial for the treatment of chronic hypoparathyroidism. The company is also developing Imapextide (MBX 1416), a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 2 clinical trial a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies for the treatment of obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana.

Key facts

Sector
Healthcare
Industry
Biotechnology
Market cap
$2.35B
P/E (ttm)
—
Forward P/E
-12.3
Dividend yield
0.00%
Beta
0.10
Profit margin
0.0%
Employees
63
Headquarters
Carmel, IN, United States
Exchange
NasdaqGS
Website

Performance

1 Month
-22.4%
3 Months
-22.4%
6 Months
+44.6%
1 Year
+269.3%
5 Years
+113.2%
$12.9452-week range$72.64
Biggest setback — last 12 months
-30.9%
12 Jan 2026 → 9 Mar 2026
Fell from $40.53 to $28.00 — its sharpest sustained decline this year.
Biggest run-up — last 12 months
+418.7%
13 Oct 2025 → 10 Aug 2026
Ran from $13.22 to $68.57 — its strongest sustained advance this year.

Price outlook — trend & volatility model

● Trend: Above long-term trend
Price sits above its 200-day average, but the shorter-term averages are not cleanly aligned above/below it.
HorizonBear case (−1σ)Base caseBull case (+1σ)
1 Month$40.22 (-17.6%)$48.82$59.26 (+21.4%)
3 Months$34.90 (-28.5%)$48.82$68.29 (+39.9%)
6 Months$30.37 (-37.8%)$48.82$78.47 (+60.7%)
12 Months$24.95 (-48.9%)$48.82$95.52 (+95.7%)
Statistical, not machine-learning: a random-walk (no assumed drift) volatility model built from this ticker's own realized price history, plus a purely descriptive moving-average trend read. Illustrative only — not a price target and not financial advice. The bear and bull cases sit one standard deviation (1σ) below and above today's price, a range that covers about 68% of the outcomes the model treats as plausible, not a 68% chance of either case. Annualized volatility used: 67.1%, blended from this ticker's own 3-month and 1-year realized price history. Base case is deliberately flat — this quantifies a possible range, not a directional prediction. See the full model, including wider (≈95%) bands →

Comparable companies

Recent headlines

Recent insider activity

Sold 370 shares at $65.77 — Azoulay Salomon, Chief Medical Officer · 2026-08-05
Acquired 28,000 shares — Smither John W, Chief Financial Officer · 2026-08-04
Acquired 71,000 shares — Hoerter Steven L., President and CEO · 2026-08-04
Acquired 12,500 shares — Mathers Edward T, Director · 2026-06-05
Acquired 12,500 shares — Pescovitz Ora H., Director · 2026-06-05
Source: SEC Form 4 filings. An "acquired" entry with no price is typically a stock award or option exercise rather than an open-market purchase. Search all insider trades →

Learn the basics

Prices and company data are delayed reference figures from public sources (Yahoo Finance, SEC EDGAR) and may be inaccurate or out of date. This page is informational only — it is not investment advice or a recommendation to buy or sell any security. Past performance does not indicate future results.